[1]李宝生,於文雪,尹勇,等.应用模拟定位机对肺癌肿块运动的研究[J].东南大学学报(自然科学版),2002,32(4):590-593.[doi:10.3969/j.issn.1001-0505.2002.04.011]
 Li Baosheng,Yu Wenxue,Yin Yong,et al.Research on motion of lung cancer with simulator system[J].Journal of Southeast University (Natural Science Edition),2002,32(4):590-593.[doi:10.3969/j.issn.1001-0505.2002.04.011]
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应用模拟定位机对肺癌肿块运动的研究()
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《东南大学学报(自然科学版)》[ISSN:1001-0505/CN:32-1178/N]

卷:
32
期数:
2002年第4期
页码:
590-593
栏目:
生物医学工程
出版日期:
2002-07-20

文章信息/Info

Title:
Research on motion of lung cancer with simulator system
作者:
李宝生1 於文雪1 尹勇2 李松毅1 于金明2
1 东南大学生物科学与医学工程系,南京 210096; 2 山东省肿瘤防治研究院,济南 250117
Author(s):
Li Baosheng1 Yu Wenxue1 Yin Yong2 Li Songyi1 Yu Jinming2
1 Department of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China
2 Shandong Tumor Hospital and Institute, Ji’nan 250117, China
关键词:
肿瘤 运动
Keywords:
lung tumor motion
分类号:
R815
DOI:
10.3969/j.issn.1001-0505.2002.04.011
摘要:
肺肿瘤随呼吸运动是制约放疗剂量提升的主要因素之一.为确定每个肺癌患者的肿瘤运动范围,用模拟定位机对肺癌病人的呼吸运动、肿瘤运动及体表标记物三者的运动进行了检测,通过瞬时傅立叶变换技术对肿瘤一系列的动态变化进行研究,并对比了肿瘤和体表标记物的运动.结果发现:不同患者间肿瘤随呼吸运动的差异较大,且肺部肿瘤与体表标记物的运动存在明显的异相性,它对于确定肺癌个体化的外放边缘具有指导意义.
Abstract:
Lung tumor motion due to breathing is one of the main factors hindering the dose escalation of radiotherapy. To evaluate the motion range of every lung cancer patient, the respiration, tumor motion, and the motion of skin marker were studied by using simulator system. Temporal Fourier transformation was introduced to convert the motion information to a static view. Motion patterns of lung cancers and skin markers were compared. The results show that tumor motion due to breathing varies significantly from patient to patient. Significant motion phase discrepancies between lung tumors and external markers have also been observed. These results will be useful in the individual design of beam margins during planning of radiation therapy of lung cancer.

参考文献/References:

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相似文献/References:

[1]李宝生,尹勇,辜嘉.应用快速CT扫描对肺癌运动的研究[J].东南大学学报(自然科学版),2003,33(6):728.[doi:10.3969/j.issn.1001-0505.2003.06.012]
 Li Baosheng,Yin Yong,Gu Jia.Research on motion of lung cancer with fast CT scan[J].Journal of Southeast University (Natural Science Edition),2003,33(4):728.[doi:10.3969/j.issn.1001-0505.2003.06.012]

备注/Memo

备注/Memo:
作者简介: 李宝生(1962—),男,副主任医师,yjmaaa@jn-public.sd.cninfo.net.
更新日期/Last Update: 2002-07-20