[1]吴巍,宁新宝,姜藻,等.低功率超声辐射LEVOVIST试剂致家兔肝脏微血管栓塞的研究[J].东南大学学报(自然科学版),2003,33(3):300-302.[doi:10.3969/j.issn.1001-0505.2003.03.013]
 Wu Wei,Ning Xingbao,Jiang Zao,et al.Formation of micro-vessel embolization in rabbit liver induced by low power ultrasound irradiation combined with LEVOVIST agent[J].Journal of Southeast University (Natural Science Edition),2003,33(3):300-302.[doi:10.3969/j.issn.1001-0505.2003.03.013]
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低功率超声辐射LEVOVIST试剂致家兔肝脏微血管栓塞的研究()
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《东南大学学报(自然科学版)》[ISSN:1001-0505/CN:32-1178/N]

卷:
33
期数:
2003年第3期
页码:
300-302
栏目:
生物医学工程
出版日期:
2003-05-20

文章信息/Info

Title:
Formation of micro-vessel embolization in rabbit liver induced by low power ultrasound irradiation combined with LEVOVIST agent
作者:
吴巍1 宁新宝1 姜藻2 郭晓远2 冯若1
1 南京大学声学研究所近代声学国家重点实验室, 南京 210093; 2 东南大学附属中大医院, 南京 210009
Author(s):
Wu Wei1 Ning Xingbao1 Jiang Zao2 Guo Xiaoyuan2 Feng Ruo1
1 State Key Laboratory of Modern Acoustics, Institute of Acoustics, Nanjing University, Nanjing 210093, China
2 The Affiliated Zhongda Hospital of Southeast University, Nanjing 210009, China
关键词:
超声 声孔效应 LEVOVIST试剂
Keywords:
ultrasound sonoporation effect LEVOVIST agent
分类号:
R454.3;R364.5
DOI:
10.3969/j.issn.1001-0505.2003.03.013
摘要:
探讨在生物体内输注LEVOVIST试剂以增强其被低功率超声辐射时微小血管栓塞形成效率的新途径.将12只成年家兔随机平均分为单纯超声、单纯LEVOVIST试剂、低功率超声幅射+LEVOVIST试剂作用组和对照组共4组进行实验; 实验样本均作常规病理组织学方法分析,实验数据均作统计学处理.实验数据显示低功率超声辐射+LEVOVIST试剂可显著增强声孔效应和血管栓塞率,靶区内89.11%的微小血管栓塞; 单纯超声辐射血管组的栓塞效果不明显,单纯LEVOVIST试剂和对照组仅有少许栓塞现象.
Abstract:
A new way to enhance thrombus formation rate in micro-vessel in vivo by low power ultrasound irradiation combined with LEVOVIST agent on organism tissue was investigated. 12 adult rabbits were divided into four groups at random: ultrasound, LEVOVIST agent, ultrasound+LEVOVIST agent and control groups. Routine pathologic histological method was used to analyze the experimental samples. The experimental results were compared statistically. The experimental date show that low power ultrasound irradiation combined with LEVOVIST agent can notably increase the thrombus formative rate reaching 89.11%, while the effect of single ultrasound group is not apparent. There is only a little thrombus formation in single LEVOVIST agent and/or control groups.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金重点资助项目(19934001).
作者简介: 吴巍(1958—),男,博士生; 宁新宝(联系人),男,教授,博士生导师, xbning@nju.edu.cn.
更新日期/Last Update: 2003-05-20