[1]程洁,周啸,李俐军,等.冠脉支架的多功能体外力学性能测试装置及实验研究[J].东南大学学报(自然科学版),2010,40(2):341-345.[doi:10.3969/j.issn.1001-0505.2010.02.024]
　Cheng Jie,Zhou Xiao,Li Lijun,et al.In-vitro test apparatus and experimental study of mechanics properties of coronary stents[J].Journal of Southeast University (Natural Science Edition),2010,40(2):341-345.[doi:10.3969/j.issn.1001-0505.2010.02.024]
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冠脉支架的多功能体外力学性能测试装置及实验研究()
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《东南大学学报(自然科学版)》[ISSN:1001-0505/CN:32-1178/N]

卷:
40
期数:
2010年第2期
页码:
341-345
栏目:
生物医学工程
出版日期:
2010-03-20

文章信息/Info

Title:
In-vitro test apparatus and experimental study of mechanics properties of coronary stents
作者:
程洁;  周啸;  李俐军;  倪中华
东南大学江苏省微纳生物医疗器械设计与制造重点实验室,南京 211189; 东南大学机械工程学院, 南京 211189
Author(s):
Cheng Jie;  Zhou Xiao;  Li Lijun;  Ni Zhonghua
Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing 211189, China
School of Mechanical Engineering, Southeast University, Nanjing 211189, China
关键词:
冠脉支架;  机器视觉技术;  力学性能;  血流动力学
Keywords:
coronary stent;  machine vision technique;  mechanics properties;  hemodynamics
分类号:
R318.11;TH77
DOI:
10.3969/j.issn.1001-0505.2010.02.024
摘要:
针对开发优良力学性能冠脉血管支架的测试需求,研究开发了一套基于机器视觉技术的多功能血管支架力学性能测试装置,并应用所研制的测试装置对自主研发的薄壁微管雕刻316L不锈钢冠脉支架介入过程中的柔顺性、径向支撑力以及支架植入后脉动流环境下的血流动力学特性等多项力学性能进行测试.测试结果表明:该支架具有良好的输送性能; 其径向支撑力为180 kPa; 该支架植入后降低了支架段血管内壁的壁面剪应力,特别是支架近前端和近后端处为低剪应力区,易导致内膜增生而出现再狭窄.测试过程表明,该测试装置满足冠脉支架的多种力学性能测试需求.
Abstract:
In order to improve the design and manufacturing of coronary stents, an in-vitro test apparatus for the measure of stents’ mechanics properties based on machine vision technique was developed. Relevant experiments were designed and performed to evaluate an independent designed thin-walled cutting tubular 316L stent with its transportation performance, radial strength during the intervention, and hemodynamics in pulsatile flow after the implantation. It is found that the stent has good transportation performance with radial strength of a maximum value of 180 kPa. It is also proved that stenting induces the reduction of the local wall shear stress, especially in pre-stent and post-stent regions, which may be a risk factor for restenosis by neointimal hyperplasia. The results show that the appartus can meet the requirement of the multiple mechanics-properties tests of stents.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介: 程洁(1975—),女,博士生,讲师; 倪中华(联系人),男,博士,教授,博士生导师,nzh2003@seu.edu.cn.
基金项目: 国家自然科学基金资助项目(50805022)、江苏省自然科学基金资助项目(BK2008280).
引文格式: 程洁,周啸,李俐军,等.冠脉支架的多功能体外力学性能测试装置及实验研究[J].东南大学学报:自然科学版,2010,40(2):341-345. [doi:10.3969/j.issn.1001-0505.2010.02.024]
更新日期/Last Update: 2010-03-20